The CENTAURI System is designed to fit today's workflow.
Predictable, transmural, and circumferential lesions
Simple to attain and confirm contact of single electrode
Non-thermal mechanism of action
Connects to multiple focal points in any configuration
Key Facts About PEF
Add more details on traditional waveforms here
Showers of microbubbles
in the left heart
Bubbles in the heart and the brain are never good. The proprietary WAVE1 waveform produced by the CENTAURI PEF System has largely eliminated
Bubbles Are Not a Concern
Non-contact: Contact or extreme proximity is required since blood is a highly conductive current shunt. Electrons follow a path of least resistance, even with PEF. A specific force range probably matters less for PEF than RF.
Monopolar is unacceptable due to muscle contraction: The Gala Therapeutics and Galaxy Medical clinical data strongly suggest otherwise. By understanding the biology and biophysics, contraction effects can be mitigated.
Galaxy's Wave1 Waveform &
PEF delivers tens of amps through a resistive tissue load. Heating cannot be avoided; control is the key.
Our testing has shown a very low heat signature using our proprietary WAVE1 waveform and dosing scheme.
Proximity & Tissue Planes
It appears that a combination of electrode proximity, tissue plane effects, and related E-field discontinuities may cause what appears to be tissue selectivity.
PEF energy utilizes high voltage, high frequency pulses to ablate tissue
Induces cellular apoptosis more than necrosis, yielding gentle cell death
Can be non-thermal, but waveform parameters and dose are critical
Extremely sensitive to tissue planes
PEF makes focal ablation better
Safer than RF because of the non-thermal mechanism of action & sensitivity of the energy to tissue boundaries
Increased safety profile will give greater confidence to deliver transmural lesions, improving efficacy
Focal lesions are deep, wide, and consistent
Faster than standard RF
Contact is critical to enable predictable lesions